Cooling caused the scaffold to lock in its temporary shape within the defect.
These results show that the RB-K or the RB-N mutant retains growth suppression activity, but the RB-KN mutant is defective in growth suppression, consistent with its defect in repressing transcription from the Cyclin A promoter (Fig. 2A).
The first acyltransferase recognized to be involved in phosphatydylethanolamine synthesis was identified based on the PlsC mutant in Escherichia coli, (named after its defect in phospholipid synthesis).
Although β-HMX has been studied thoroughly as to its explosive properties, only a small amount of work has been performed in relation to its defect properties and mechanical properties.
All reported sequenced alleles of unc-18 have a molecular defect in either exon 4 or exon 9 [ 31]; however, sy671 has its defect in exon 8.
In control conditions, ABA contents were significantly higher in esk1 mutants than either wild type or aba3-1, the latter being due to its defect in ABA biosynthesis [17].
Kanagawa, M. et al. Identification of a post-translational modification with ribitol-phosphate and its defect in muscular dystrophy.
As previously reported, in a wild-type background, the U2-IIc allele confers a slow growth phenotype (Figure 2C) consistent with its defect in splicing (data not shown).
In further support of this idea, our previous work demonstrates that a Tax mutant, TaxM22, is capable of Tak1 activation despite its defect in IKK activation [ 34].
