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Musicians typically take 5 to 20 milligrams in isolated doses.
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There is very little evidence on the direct in vitro effects of these agents on cardiac contractile function in sepsis, and the isolated, dose-dependent effects of these induction agents on myocardial excitability, contractility, coronary flow, and oxygen utilization in a septic heart are still unknown.
Lingohr et al. (2002) reported that DCA-induced glycogenosis in isolated murine hepatocytes was dose related, occurred at very low doses (10 μM), occurred without the presence of insulin, was not affected by insulin addition, was dependent on phosphatidylinositol 3-kinase activity, and was not a result of decreased glycogen breakdown.
Both our in vitro and in vivo data in the current study support this suggestion; we found that adenosine significantly upregulates A2AR expression levels in isolated PMC in a dose dependent manner.
2) Amphetamine dose-dependently induced USVs in isolated wild-type males, but did not induce USVs in females or M5 KO mice.
In isolated porcine skeletal muscle mitochondria, stimulated respiration decreased at high doses (50 and 100 μg/mL LPS).
Previously, we showed that relaxin dose-dependently induces matrix metalloproteinase (MMP) expression in isolated joint fibrocartilaginous cells.
AEIA exhibited a dose-dependent (∼400 μg/ml) increase in cell viability against Dox (1 μM) in isolated rodent hepatocytes.
Trouble flared in isolated areas.
Specifically, BNO 1095 dose-dependently inhibited oxytocin-induced uterine contractions in a rat dysmenorrhea model in vivo and drug-induced contractions in isolated human and rat uterine tissue in vitro.
Biodistribution studies at 3 months postinjection showed no vector in optic nerve or visual centers in the brain and only isolated non-dose-related detection in other organs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com