Sentence examples for in internalisation from inspiring English sources

However, the results from our fluorescent microscopy show most of the 'PDTR'-specific HuHMFG-1 antibody rapidly internalises within 15 min, again demonstrating the importance of fine specificity in internalisation.

In internalisation experiments, differences induced by ADT were evident.

Binding of proteins to lipid rafts may result in internalisation of such proteins into cells.

Activation of RTK kinase activity results in internalisation of activated receptor complexes resulting in both signal propagation and degradation.

To further elucidate the endocytic process involved in internalisation of the toxin, we tested dimethylamiloride (DMA) (200 µM) (Fig. 3D), a potent blocker of Na+/H+ exchange, which inhibits macropinocytosis.

These changes in phosphorylation appear to result in internalisation of connexins into the cytoplasm, disassembling the gap junctions and cutting off communication between cells (Yang et al, 2001).

The Ptch binds to the Hh proteins, resulting in Ptch internalisation in endosomes and lifting Ptch-mediated repression.

These mutations affect several phosphorylation sites (Supplementary Table 2; Fig. 1), which may result in differences in receptor internalisation and regulation of its activity (Hicke et al., 1998).

Furthermore, in the internalisation assay, protein might be internalised and return to the same sites via exocytosis.

The effect of albumin fragments (FRALB-C) and selected albumin-derived peptides on the internalisation of In-albumin, In-minigastrin, In-exendin and In-octreotide by megalin-expressing cells was assessed.

Whether syndecans are involved in general receptor uptake or in the internalisation of specific receptors remains to be determined.