Follow-up segregation studies on affected family members (if available) can play a key role in the interpretation of variants and, in informative families, can provide pivotal information regarding the causal role of a putative mutation.
An alternative to using our heuristic that may recapture some lost variants that were slow to converge in informative samples would be to use diagnostics for information loss based on the observed-data observed information matrix such as condition number or the spectral decomposition approach suggested by Meng and Rubin (1991).
These, too, are related in informative if perfunctory fashion, with the occasional sentimental exhortation tossed into the mix ("You have to let those you love know that you love them... before it's too late").
By the time "Aida" was given its European premiere at La Scala in Milan in 1872, Dino Rizzo points out in informative booklet notes, Verdi was well aware of the Milanese taste for elaborate orchestral music.
"Staging this series of forums is a truly innovative idea that will allow everybody who is affected by or interested in mental health to take part in informative, frank and relaxed discussions," she says.
In informative program notes the Baroque violinist and Juilliard faculty member Robert Mealy reports that Monteverdi has again entered the musicological speculation as the composer of this ravishing finale.
They are finding ways to offer consumers exposure to their brands in informative and entertaining ways.
By studying the PLS coefficients in informative 3-D contour plots, ideas for the synthesis of new compounds could be generated.
The importance of rest, hydration and nutrition are integrated into cross training classes and reinforced in informative monthly newsletters.
The imprinted expression of transcripts in the human KCNQ1 cluster was analysed in informative hES and EB-TS cell lines and first trimester placenta.
Maternal plasma DNA analysis was performed by comparing the ratio of digestion-resistant HLCS to fetal-specific rs6636 SNP allele in informative samples.
