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It is effective in indigestion remedies and antisyphilitic drugs.
A deficiency of vitamin B12 often causes defective function of the intestine, resulting in indigestion and sometimes constipation or diarrhea.
This study provides a rationale for the medicinal use of Viola betonicifolia in indigestion and constipation.
The present study was aimed to provide ethnopharmacological basis for the medicinal use of Viola betonicifolia whole plant in indigestion and constipation.
ACh is a neurotransmitter of the parasympathetic nervous system and is known to cause gastrointestinal stimulation through the activation of muscarinic receptors [ 17]; hence, the presence of ACh-like constituents explains its medicinal use in indigestion and constipation.
However, the plant has not been studied for its medicinal use in indigestion or constipation except a preliminary in-vitro study showing a cholinergic activity on the part of another species (Fumaria indica) of this genus [ 7].
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In the GSRS, test-retest reliability was acceptable in the Indigestion and Constipation domains in most language versions.
Intraclass correlation coefficients were high (> 0.7) for the Hungarian, Polish and Spanish versions of the GSRS in the Indigestion domain, for the Hungarian version in the Diarrhoea domain, and for the Afrikaans, Hungarian, Polish and Spanish versions in the Constipation domain.
Internal consistency was also high in the Indigestion, Diarrhoea and Constipation domains of the GSRS in all language versions.
There were no differences between PPI partial responders and treatment-naïve patients in the Indigestion and Diarrhea domains, but Constipation domain scores were higher in partial PPI responders than in the treatment-naïve group before PPI therapy.
Its acquisition of American Stores, which more than doubled its store count to 2,600, resulted in financial indigestion.
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