Sentence examples for in humans phase from inspiring English sources

Phase shifting: In humans, phase shifts in response to very bright light do not differ significantly between older and younger subjects, at least for phase delays [ 19, 20].

We conducted a first-time in humans phase I safety trial using the pGA2/JS2 (JS2) HIV-1 DNA priming vector expressing Gag, Pol, Env, Tat, Rev, and Vpu.

In humans, phase I HIV and cancer studies demonstrated the safety and biologic activity of single or repeated doses of nonglycosylated recombinant human IL-7 (rhIL-7) [ 12– 15].

There are three alternative approaches to conducting initial "confirmation of antimalarial activity in vivo in humans" phase 2 studies which are safer than first use in patients with symptomatic falciparum malaria.

5 9 In broad terms, drug development begins with discovery and preclinical laboratory research, before moving on to clinical development, starting with first testing in humans (phase I clinical trials) and continuing until regulatory review and approval.

Molckovsky, A. & Siu, L. L. First-in-class, first-in-human phase I results of targeted agents: highlights of the 2008 American Society of Clinical Oncology meeting.

Mukai, H. et al. A first-in-human phase 1 study of epirubicin-conjugated polymer micelles (K-912/NC-6300) in patients with advanced or recurrent solid tumors.

Gertz, M. A. et al. First-in-Human Phase I/II Study of NEOD001 in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction.

Schultheis, B. et al. First-in-human phase I study of the liposomal RNA interference therapeutic Atu027 in patients with advanced solid tumours.

This multicentre, open-label, first-in-human, phase I study was conducted at nine centres in the USA, Canada, and the UK (BMA117159; NCT02064387).

Sivapalasingam, S. et al. Safety, pharmacokinetics, and immunogenicity of a co-formulated cocktail of three human monoclonal antibodies targeting Ebola virus glycoprotein in healthy adults: a randomised, first-in-human phase 1 study.