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To evaluate the stromal concentration of 2 commercially available transepithelial riboflavin 0.1% solutions in human donor corneas with the use of spectrophotometry.
To evaluate and compare intraocular pressures (IOPs) during flap preparations performed using 2 femtosecond lasers and a mechanical microkeratome in human donor globes.
Based on results obtained in murine models we have explored the CD95-mediated activation-induced cell death (AICD) strategy to selectively deplete alloreactivity in human donor T lymphocytes in vitro.
It has been reported that phosphorylation of H2AX (referred to as γ-H2AX) increases with age in human donor PBMCs [30].
Lutein is present in human donor eyes as early as 17 22 weeks gestation [ 1, 9].
Nonetheless, safety studies in human donor corneas would be advisable before any application of the study procedure to human keratoplasty.
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Elevation in vessel density was observed in response to treatment, which may be due in part to elevations in human (donor -derived cytokines EGF, VEGF andonor -derived
Dual colour flow cytometry with Annexin-V-FITC and propidium iodide (Nexin Research, Kattendijke, The Netherlands) was used to probe apoptotic and necrotic fractions in NB4 cells and in human donor-derived PBLs exposed to khat extracts for 8 h.
This study provides new insight into the transcriptional effects of HDACi in human donor-matched normal and transformed cells, and implicates specific molecules and pathways in the tumor-selective cytotoxic activity of these compounds.
Slightly increased variation in human donors is a combination of biological and technical variation.
We came across a large variation in autophagy levels especially on induction with starvation, in human donors, which may be due to diurnal rhythm of each donor or differences in daily routines.
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