Sentence examples for in human circulation from inspiring English sources
DHEA is abundant in human circulation, but exogenous DHEA has poor oral bioavailability and is primarily metabolized into sex steroids, which yield the corresponding side effects rather than the desired benefits [15], [16].
Oxidation via the action of the enzyme CYP7B leads to the 7-hydroxy derivatives of C-19 steroids [24], [25], which are collectively present in low nanomolar concentrations in human circulation and are not readily metabolized to potent androgens or estrogens.
Steady flow models for blood flow analysis in human circulation are very complex.
In late 2012, detection of numerous exogenous RNA sequences in human circulation was reported [ 101].
Gas6, the protein product of the growth arrest specific gene 6, is present in human circulation at subnanomolar concentrations.
Here, the authors evaluate the effects on cell differentiation and function of OXPHOS-targeting xenobiotics at concentrations that have been reported in human circulation.
DHEA and its sulfate ester DHEAS are the most abundant steroids in the human circulation and accumulate in adipose tissue at even greater concentrations (10 15 times circulating levels) (4, 17).
Low-density lipoprotein (LDL) particles, the major carriers of cholesterol in the human circulation, have a key role in cholesterol physiology and in the development of atherosclerosis.
However, in the human circulation, there are localized feedback mechanisms in certain vascular beds that operate jointly with the baroreflex to regulate pressure and flow in areas such as the cerebral, coronary and renal circulations.
Half-life values of β-END vary from 2 to 10 min in the peripheral circulation of rat and rabbit and between 20 and 50 min in the human circulation [ 115, 141, 142], while in the CNS, degradation of β-END hardly occurs at all [ 141, 142].
Plasmodium falciparum is responsible for the majority of malaria attributed deaths in sub-Saharan Africa although the parasites are also frequently present in the human circulation without causing malaria symptoms.
