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More generally, it will contribute to generate more insight in human affect in virtual psychosocial interviews.
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Recently it was reported that deletion in mice of the region orthologous to the 9p21 CAD interval in human affects the expression of the nearby cdkn2a and cdkn2b genes as well as the properties of proliferation of vascular cells [30].
In addition, studies are required to gain further insights on how leptin mutations, not only this V145E mutation, but also other mutations identified in humans, affect the binding to and subsequent activation of leptin receptor.
Consistently, mutations in the WNT3 gene in humans affect limb development, resulting in tetra-amelia (Niemann et al., 2004).
Mutations in desmosomal plaque components in humans affect the myocardium as well as the epidermis with its appendages (Table 1).
Many of the genomic imprinting disorders identified so far in humans affect growth and development [ 21, 25, 26].
Mutations of the CFTR gene in humans affect functioning of the chloride ion channels in cell membranes, leading to cystic fibrosis [ 22, 23].
For instance, germline mutations of adenomatosis polyposis coli (APC) gene in humans affect primarily the colorectal epithelial cells, predisposing them to adenoma formation [ 5– 7].
Furthermore, hearing loss due to inner ear affection is a major characteristic in humans affected by S. suis meningitis [ 1].
It is possibly the most common cestode found in humans, affecting chiefly children.
This study was designed to investigate a possible relationship between idiopathic pericardial effusion in dogs and viruses most commonly encountered in humans affected with viral pericarditis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com