Exact(33)
Schizophrenia involves alterations in hippocampal function.
Several other connections play important roles in hippocampal function.
As with the memory theory, there is now almost universal agreement that spatial coding plays an important role in hippocampal function, but the details are widely debated.
The EphA receptors have roles in hippocampal function and memory formation.
Our objective was to examine changes in hippocampal function that become apparent in parallel with spatial learning deficits.
Based on these properties it has been proposed that they might play unique roles in hippocampal function [26] [28].
Similar(27)
Moreover, results also stress the role of the LPA1 receptor in hippocampal functioning.
Together, these results suggest that individual differences in conditioned fear expression may be mediated partly by enduring differences in hippocampal functioning.
Although is generally accepted that neurogenesis participates in hippocampal functions (e.g., [23], [24]), evidence for this connection still remains inconclusive (e.g., [25]).
Given the age-related decline in hippocampal functioning in the absence of dementia, our demonstration of a loss of markers that at least in rodents are related to particular aspects of brain plasticity deserves further analysis.
The present report investigates the intrinsic ability of Dyrk1A+/− mice to form spatial memories, a function that is disturbed in patients with mental retardation and relies on particular weakness in hippocampal functions.
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