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The implementation and roll-out of an updated technology would have additional costs, thus a key recommendation would be to test capabilities in further trial studies, with a small number of units.
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To achieve this, we strongly urge the design of and participation in further trials.
Koppe and Loomba agree that if DNP does prove to be safe and effective in further trials, it could win approval from FDA, despite its history.
Therefore, the findings that marathon running increases the levels of this macrophage-specific marker of immune activation is of note and should be considered in further trials on the relationships between inflammation and strenuous exercise.
The response rate is remarkably high for a trial whose goal is to test safety, Dezube says; it could become even higher when the optimal dose is determined in further trials, which are scheduled to begin this spring.
lactis BFE 6049 showed the best potential and were thus selected for use as starter cultures in further trials with the objective to improve their technological performance and to optimise the sensory features of fermented milk obtained.
If SCYX-7158 pans out in further trials, "it will be the first new, orally active treatment for sleeping sickness in the past 30 years," says Robert Jacobs, a medicinal chemist at SCYNEXIS and lead author on the new study.
In the very first trial a piece of dry food was positioned on the other side of the barrier to get the animal motivated to participate in further trials.
This will be evaluated in further trials.
Therefore, the efficacy of higher doses of NAC should be investigated in further trials.
The potential role of longer-term therapy remains to be evaluated in further trials.
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