Sentence examples for in further differentiation from inspiring English sources

Altogether these observations - i.e. low frequency of hematopoietic colonies, limited proliferation, bias toward erythropoiesis and absence of adult globin synthesis - suggest that ESC differentiated in vitro exhibit a block in further differentiation that prevents them to reach the same stage than CB-HSC.

The multiple developmental potential of these cells was also confirmed in further differentiation cultures to mature cell types.

The different enrichment patterns are thought to reflect the developmental stage at which the somatic allele arose (stem cell vs. multipotent progenitor or lineage committed progenitor) and the importance of WASP in further differentiation, proliferation and survival of the affected lineage(s).

(F ) Pdx-1 immunostaining (pancreatic progenitor marker) showing expression in further differentiation of ADE cultures.

These differences between osmolytes can potentially be used in further differentiation of hydrophobic and osmophobic effects within DSEs (6).

Our data suggest that these cells are less efficient in further differentiation to derivatives of the ventral foregut such as pancreatic or hepatic progenitors.

These speculations are further corroborated by the observations that mature oligodendrocytes found in active lesions slowly disappear from established lesions [ 208], and that the OPCs found in late demyelinated lesions seem to be impaired in their further differentiation to mature myelin forming oligodendrocytes [ 31, 94].

Our results expand this model and suggest that Jmjd3 fulfills a biphasic role in neurogenesis, regulating the neurogenic program both in the transition from ES to NS cells and in the further differentiation of NS cells down the neuronal lineage.

The lymphatic system is commonly divided into the primary lymphoid organs, which are the sites of B and T cell maturation, and the secondary lymphoid organs, in which further differentiation of lymphocytes occurs.

These results show that ATF2 is specifically expressed, between E11.5 and E12.5, in all visceral and somatic motoneurons we examined and may thus play a role in the further differentiation of these neurons.

In the early Pleistocene, further differentiation in Hylobates occurred on Borneo and Sumatra, and in Hoolock on the mainland which is on a similar time scale when macaque species diverged [ 44, 45], and which might has been triggered by the shrinking of forest habitats due to cold phases [[ 74], but see [ 58]].