But thankfulness or gratitude could have a bigger, more ongoing place in our lives, even if it is done in small, frequent doses.
A well-built game is, in essence, a series of short-term feedback loops, delivering assessment in small, frequent doses.
While the daily dosage of the standardized ginkgoflavonglycosides and Ginkgo biloba is the same, there could be a benefit to taking the G. biloba in more frequent doses.
To ensure maximum effect and minimise adverse events, it has been advised that haloperidol should be administered in small, frequent doses (0.5 to 1 mg every two to four hours) [ 17, 18].
Measures to reduce N leaching losses in forests include minimising vegetation control at planting, maximising tree N uptake by correcting other growth-limiting factors, facilitating rapid site revegetation after harvesting, avoiding harvesting in winter/early spring, and applying fertiliser to coastal sands or other sites prone to high N leaching in small, but frequent, doses.
In patients with CLL, rituximab has been administered in higher or more frequent doses, up to 2250 mg/m2 weekly [ 11] or 375 mg/m2 three times weekly [ 12].
But giving Venofer, the iron drug, in smaller and more frequent doses would increase needle use, violating that policy.
Studies have shown that vancomycin is much better tolerated when it is given in smaller and more frequent doses [ 20].
It is well known and appreciated that many patients, especially those with advanced PD, will require frequent doses in excess of 800 mg a day.
These recent trials in CXMDj utilised very high and frequent doses of systemically delivered antisense oligonucleotides; additional work, in particular, improving delivery, efficacy and reducing dose, frequency and the potential for toxicity is very important for similar systemic therapeutic trials in humans.
