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One example is the hubgene ACSL1, which is known to be involved in four pathways: fatty acid metabolism, PPAR signaling pathway, peroxisome, and adipocytokine signaling pathway.
Sz and MF are defined by aberrations in four pathways: (1) evasion of activation-induced cell death, (2) TH2-biased lymphocyte differentiation, (3) TGFβ receptor expression and (4) modulation of TNF receptor ligands (reviewed in Dulmage et al).
In fact, examining the dataset from GPL17 discussed in the methods performance on pathways section we observed that this situation occurs in four pathways on average in each experiment.
Among all the biological processes (Table 3) and top functions (Table 4), shown to be regulated during PrV infection, we examined in greater detail genes differentially expressed in four pathways i.e. immune response, apoptosis, nucleic acid binding and actin cytoskeleton (Table 5).
The gene targets of core DE miRNAs have functions related to gene expression and general cellular metabolism (P < 0.05) and are enriched in four pathways of lipid metabolism (3-phosphoinositide biosynthesis, 3-phosphoinositide degradation, D-myo-inisitol-5-phosphate metabolism and the superpathway of inositol phosphate compounds).
By contrast, genes in "Carbohydrate metabolism" pathway were only significantly enriched in the root tip region, and genes in four pathways, "signal transduction", "Environmental adaptation", "Immune system" and "Sensory system" were overrepresented in the basal roots but not in the root tips under Al stress (Table 3).
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The results appear in two "Pathways to Paris" reports released today — one for the 10-member Association of Southeast Asian Nations (ASEAN), the other for selected countries in Latin America (LAM).
Microbiologically (R -3-HB can be synthesized in two pathways.
It inhibits cell killing by HIV in two pathways: inhibition of both reverse transcriptases as well as processes of cellular fusion.
In particular, the decomposition of hydrazine takes place in two pathways, which are given as follows: (i) Complete decomposition (basic medium) N2H4 → N2 (g) + 2H2 (g) (ii) Incomplete decomposition (acid medium) 3 N2H4 → 4NH3 + 2N2 (g) .
We detected consistent and significant mRNA changes in two pathways, chromatin structure and cell adhesion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com