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It was hypothesized that application of the patches would significantly alter perfusion in fingertips.
Now Lesniak and Marshall et al. have revealed that structure determines function in a type of mammalian touch receptor called the slowly adapting type I receptor, which is concentrated in fingertips and other areas of high tactile acuity.
Skin blood flow was measured in supine subjects at the lateral epicondyle (typical FM tender point [ 8]), in fingertips II and III (that is, of the forefinger and middle finger) and in the lower arm (control point) using the laser Doppler technique (PeriFlux PF3; Perimed, Järfälla, Sweden), as described elsewhere [ 12].
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My guess is the verb will be replaced not by punch, poke or jab, which suggest dialing in anger, but by key, press or tip, as in "fingertip".
We performed a regression analysis between the changes in fingertip synchrony and the changes in brain activity from pre- to post-training sessions.
During fMRI acquisition, subjects performed a constant probing task, which involved continuous contact between the index fingertip and the interface and rhythmic increases and decreases in fingertip force (1.6 Hz) to probe stiffness.
Per cent carboxyhaemoglobin (%HbCO) in fingertip capillary blood was measured using the same OSM3 hemoximeter (Radiometer, Copenhagen, Denmark) before and 7 min after administration of the CO dose.
Visual feedback reduced the variability in fingertip-trunk timing, an effect not observed in healthy subjects, whose timing proved to be independent of vision.
We measured the concentrations of acetone in the breath using gas chromatography-mass spectrometry and β -hydroxybutyrate in fingertip blood collected from 99 patients with diabetes assigned to groups 1, 2, 3, 4, or 5 according to urinary ketone concentrations.
In contrast, skin biopsies in the same participants showed that the intraepidermal nerve fiber density is lower in the fingertips than in the hand dorsum.
"Touch begins in the fingertips but ends in the brain," Dr. Srinivasan explained.
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