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More study may be required to determine if this approach results in faster resolution than monotherapy, or reduces the need for surgical intervention.
There is a suggestion that pulsed-dose methylprednisolone, in addition to aspirin and IVIG as primary therapy results in faster resolution of fever, more rapid improvement in inflammatory markers, and shorter length of hospitalization.
Conclusions Treatment of acute KD with IVMP plus ASA/IVIG, compared with ASA/IVIG alone, resulted in faster resolution of fever, more rapid improvement in markers of inflammation, and shorter length of hospitalization.
The rationale for the use of steroids is that they result in faster resolution of disc oedema, reduced compression of optic nerve head capillaries and thus improved perfusion and some recovery of surviving axons [ 20].
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For tuberculous pleural effusion there is some evidence for adjuvant corticosteroids resulting in a faster resolution of pleural effusion at 4 weeks, but no difference in residual fluid at 8 weeks or death rates between corticosteroid and non-corticosteroid groups [ 66].
"It also is likely to lead to faster resolution in those unfortunate situations where foreclosure is inevitable.
Also, further analysis showed that patients treated with DrotAA exhibited a faster resolution in cardiovascular and respiratory dysfunction [ 3].
14 From a pharmacological perspective, the findings imply that although IFNβ-1b successfully decreases the formation of new lesions, it has no effect in promoting a better or faster resolution of existing CELs once these have been formed.
We found that supplemental oxygen use was not associated with faster resolution of SP in HO and MO groups.
While the relative sedating effects of haloperidol versus quetiapine are not well quantified, if haloperidol has the greater sedative effect, the fact that nearly twice as much "as needed" haloperidol was administered on average to the placebo group may also account for the faster resolution of agitation in this group.
"We think it would lead to a faster resolution to have everything in one court," said Stephen Neuwirth, a partner of David Boies of Armonk, N.Y.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com