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Even with a high confidence level (p < 0.001), 78% of the expressed genes (24,670) varied in expression with respect to the duration of cold treatment and 46% (14,617) varied in expression with respect to genotype.
The genes, exhibiting ≥2-fold change in expression with FDR ≤0.01, were considered as 'differentially expressed' and listed.
The genes, exhibiting ≥2-fold change in expression with p value ≤0.01, were considered as 'differentially expressed' and listed.
For example, module M21 was highly expressed in neocortical regions, and showed a slight increase in expression with time (Fig. 4A).
The genes, exhibiting ≥2-fold change in expression with the false discover rate (FDR) ≤0.01, were considered as 'differentially expressed' and further examined to identify affected pathways.
The genes exhibiting ≥2-fold change in expression with FDR ≤0.01 in three biological replicates were defined as 'differentially expressed' and used for the Gene Ontology (GO) enrichment analysis.
Ostensibly direct in expression, with strong links to Russian music of the 19th century, it is fathomless in its ironies.
Transcripts associated with the Cyp2a5, Mb, Sln, Scgb3a1, and Plunc genes in the lungs and the Clec2d, Wsb1, Mup4, Acaa2, and Mpo genes in the liver showed a monotone increase or decrease in expression with the absorbed dose.
In our set, the majority of significant genes exhibited a decrease in expression with advancing age.
There were 1,029 genes (P≤0.01) that were significantly changed in expression with age in the heart.
For hierarchical analysis, genes with greater than two fold changes in expression with 250 nM ganetespib were clustered using established algorithms in Cluster [50].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com