Sentence examples for in expression of functional from inspiring English sources
Although this modification did not affect BCRP function, it may be involved in expression of functional BCRP.
Ca2+ imaging showed that differentiation from BrdU+/TuJ1− to BrdU−/TuJ1+ cells was accompanied by a shift in expression of functional receptors for neurotransmitters from cholinergic and purinergic to predominantly GABAergic and glutamatergic.
This would predict that heterozygotes for this mutation show a 50% reduction in expression of functional Na+ channels.
These results suggest there is a general increase in expression of functional hERG protein on the cell surface of all cells examined at the lower temperature.
For comparison of metatranscriptomes with low replicate numbers, random sampling of reads from the metatranscriptome has been used to create sub-metatranscriptomes that can be repeatedly compared to gauge the probability of observing differences in expression of functional categories between communities due to random chance [ 14, 16].
Here, we selected two mutations from either end of the spectrum: we report that the dysfunctional phenotype of point mutation L860P [14,15] was accounted for by a change in protein stability, which resulted in a drop in expression of functional channels.
D to JH rearrangement efficiently occurs on both alleles, however, allelic exclusion ensures that VH to DJH recombination results in expression of a functional heavy chain (HC) from only one of the two alleles [4].
Table 2 provides a summary of the changes in expression of selected functional categories of TC-specific genes that are known to be central to TC development and function.
Nevertheless, the assays showed consistent differences in expression of specific functional gene groups that are likely to relate to the observed differences in infection phenotype between the exposed and control lines.
Peripheral axotomy results in a decrease in the expression of functional Nav1.8 channels and TTX-R currents in C-type DRG neurons, suggesting a basis for the altered electrical properties observed after peripheral nerve injury [ 13].
A pathway approach has been able, for example, to identify a coordinated decrease in the expression of functional signals in human diabetes [ 16].
