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In this case, the trend in CSTD directly reflects the trend in exposure; therefore, exponential fitting of CSTD implies the assumption that intake is declining exponentially.
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Incrementing the slice thickness in sequential scans would result in an increase of dose exposure, therefore jeopardizing the advantages of the sequential scan.
As previously reported [6], [30], SOD concentrations were particularly low in severe asthma subjects, blunting the difference between ETS-exposure and non-ETS exposure in this group; and ETS exposure therefore had the most noticeable impact on SOD activity in non-severe asthmatics (SOD activity U/ml serum in non-severe asthma: non-ETS (n = 186), 17.7±0.9, ETS (n = 82), 14.8±1.0, p = 0.02).
Urinary arsenic levels are good indicators for recent exposure therefore, differences in maternal urinary arsenic level by arsenic exposure categories are not likely to be the effect of changing drinking water sources.
Insufficient contrast in exposure may therefore explain why we were unable to detect any adverse effects of our localised traffic pollution markers in this study population.
Stronger and enduring extinction memory generated in exposure therapy is therefore an important aim to better protect from return of fear phenomena.
The main challenge to pooling studies using meta-analytical techniques is often thought to lie in the difficulties of combining studies with differences in exposure assessment, and therefore in obtaining comparable indices for meta-analyses.
By contrast, carriage of N. meningitidis peaks in young adults (9 ), which implies a difference in antibiotic exposure and therefore in the selection pressure borne by these bacteria, as young children are treated more frequently than young adults.
In humans, seasonal patterns of school attendance generate seasonal fluctuations in disease exposure and, therefore, specific immunity that modulate outbreak probability [2], [12].
17, 24 We investigated whether the difference in body weight between Japanese patients and the overall SELECT study population resulted in differences in exposure to lenvatinib, and therefore could possibly explain the observed differences in safety profile.
Temporal and spatial trends in pharmaceutical exposure could therefore potentially be traced.
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