Sentence examples for in existing trial from inspiring English sources

They do not mention publishing abandoned trials and ignore responsibility for correcting reporting biases persisting in existing trial publications.

Despite the current evidence, exercise is clearly underutilized due to several barriers and knowledge gaps in existing trials that include appropriate population identification, design, and outcome measures selection.

The aim of the study was to explore the perspectives of stakeholders concerning the acceptability and practicality of nesting trials of recruitment methods in existing trials.

A possible explanation for some of our findings may be the lack of adequate power in existing trials to detect effects of aspirin, either because the efficacy of aspirin was moderate to low in itself or because diabetic status was an effect modifier.

9 10 Also, meta-analysis of published aggregated data cannot provide information on which subgroups of women might be most likely to benefit from elective single embryo transfer or present data on important outcomes such as the birth of a healthy singleton baby at term, which have not been reported in existing trials.

To be useful a single-group study should have both adequate sample size and duration of drug exposure that is both longer than the exposure in existing trials (e.g. where trials range from a few weeks to several months but single-group studies report a year or more of exposure) and long enough for AEs that take time to develop to occur (e.g. cancer).

One study involved members of the public, and another patients participating in an existing trial.

In line with existing trial protocols of ivabradine in HFrEF aiming for a heart rate target of 50 to 60 bpm, eligible participants were randomly assigned through block randomization to receive either ivabradine 7.5 mg twice daily or matching placebo tablets for 2 weeks (period 1).

This paper discusses, and applies four approaches of analyzing non-inferiority trials with multiple events, by using data from an existing trial in which subjects with breast cancer could experience local recurrence, distant recurrence, death, or a combination of these events.

As trials of this nature in these types of settings are unlikely in the future, a pooling of existing trial datasets may offer the best opportunity to identify principles and particular populations which may gain or lose most in ARV retreatment choices after failure of ART, MDR-HIV and limited retreatment options.

22 28 Higher doses of vitamin D than were used in the existing trials may be needed to suppress bone turnover if calcium is not co-administered.