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In excessive doses, it can thicken the blood, causing strokes or heart attacks.
The drugs were laced with lethal quantities of an antimalarial drug and administered in excessive doses.
Beneath her dress were elaborate Spanx and a leotard, reading "Bye Dave!" Irony can be as cloying as gushiness, in excessive doses.
Government rules also ban drugs that are used in excessive doses or duration, even if patients are found to have a condition for which the drug is appropriate.
This may be caused by severe acute or chronic lung disease, such as pneumonia or emphysema, or by certain medications that suppress respiration in excessive doses, such as general anesthetic agents.
Long-term use can, according to Graham, lead to carpal tunnel syndrome (the compression of nerves in the wrists, which causes incessant tingling), raised blood sugar levels (which can trigger Type 2 diabetes), heart failure and – in excessive doses – gigantism, the disproportionate growth of body parts.
Similar(49)
Large variation in the body contour results in excessive dose variation.
The risk here of megadoses is magnified because these vitamins, A, D, E and K, are stored in the body in fatty tissue and can accumulate to toxic levels if excessive doses are taken chronically.
Finally, continuous administration of propofol may cause clinically significant hypertriglyceridemia in patients with disordered triglyceride metabolism, or in patients receiving excessive doses of propofol or parenteral lipid supplements.
Hayes and coworkers [ 6] suggested that survivors from septic shock are characterized by an ability to increase D O2 and V O2, whereas nonsurvivors do not have sufficient physiologic reserve to do this, and in such patients excessive doses of vasopressors or fluids worsen an already bad situation.
It is well recognized in mammalian systems that excessive doses of an otherwise apoptotic stimulus (e.g., heat) can kill cells by non-programmed assault that cannot be influenced by any genetically encoded intracellular factor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com