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Reliably predicting whether a drug candidate is likely to be an HLA binder at a given variant constitutes a potentially valuable knowledge in evaluating the likelihood of an associated ADR event in a subpopulation of patients.
Using a method assuming a single breakpoint was shown [37] to perform as well or better than 14 different recombination detection methods evaluated by Posada and Crandall [72] and is particularly well suited for relatively short alignments like the one studied here where one is interested in evaluating the likelihood of recombination at a specific location along the sequence.
A history of influenza vaccination is not helpful in evaluating the likelihood of anthrax.
The optimization procedure is identical to the standard Poisson model with an exception in evaluating the likelihood in Equation (11).
In conclusion, these data suggested that prolonged APTT + normal PT + PC < 100 × 10 cells/L is useful in evaluating the likelihood of DF and/or DHF.
Although the risk of polio resurgence following certification is considered remote [ 52], the sensitivity of global surveillance is of critical importance in evaluating the likelihood of interrupting poliovirus transmission and disease freedom.
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"All the rest are just evaluating the likelihood of success".
Evaluating the likelihood of such a scenario is heuristically challenging.
The next step in evaluating the extended logistic-normal likelihood will be to code it into stock assessment programs, and some of the technical problems associated with this step are discussed.
Estimates of likelihood ratios are powerful tools in evaluating the clinical usefulness of a screening test, as likelihood ratios are not affected by the prevalence of a disease.
Likelihood ratio tests were included as performance indices in evaluating the test methods.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com