All equivalent solutions in a trace are composed by the same reversals but in different orders.
The main premise of the new method is in recognizing that while many equivalent solutions exist for the dynamic flux estimation, the subsequent flux-based regression will give parameter values with different goodness-of-fit, as measured by ΦC or ΦS.
Although, in most situations, maximization of rate and yield give equivalent solutions, Schuster presented interesting examples in S. cerevisiae and Lactobacilli where the two maximizations are not equivalent.
The underlying principle is that equivalent problems have equivalent solutions.
We found eight equivalent solutions.
In the present study, a 50 mg/mL solution was initially prepared and then diluted to obtain equivalent solutions of 25 mg/mL.
To decode the list presented in Figure2 and obtain its equivalent solution in the solution space, we start from the beginning of the list and schedule the first operation.
Importantly, the algorithm produces a robust solution for each seriation run (in other words, equivalent solution is produced upon repeated seriation of the same data set).
Both of these approaches result in equivalent steady state solutions because adding extra reactions extends linear pathways that each contain a species that exits the system.
This local increase in concentration is higher than the equivalent solution concentration containing the same amount of free ligand, as the scaffold immobilizes the ligand in a defined volume.
