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The eMPC algorithm achieved significantly better results compared with the other two protocols in the majority of the most important parameters (Table 2): in effectiveness (time to target range), in efficiency of glycemia management after reaching the target range (mean glycemia, time in target range, time in risk of hyperglycemia, and time in hyperglycemia), and in sampling interval.
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Unlike chemotherapy, which can diminish in effectiveness over time, oncolytic viruses multiply in the body and gain strength as the infection becomes established.
These high ROI estimates are based on the assumption of no decay in effectiveness over time and no employee turnover.
While initially successful at cutting and homing, both declined in effectiveness over time due to the evolutionary instability of the modular repeats inherent to those proteins.
This format of care delivery, with its group dynamics, provides theoretical upsides in cost-effectiveness, time efficiency, peer-to-peer teaching, and peer-motivated behavior change (11).
Uncertainties in BMP effectiveness over time may result in overestimating long-term efficiency in watershed planning strategies.
Most research shows that means of surveillance alone don't have a cost-effective result in general, and that they often diminish in effectiveness quite quickly over time.
In contrast, on a 5-year horizon, the lower intervention costs of the Web-based intervention when compared to the printed intervention do outweigh the loss in effectiveness over this short time horizon.
First, we can control for different study characteristics when investigating which ALMP types are associated with significant or insignificant impact findings, simultaneously addressing such issues as methodological differences or changes in programme effectiveness over time.
A decrease in vaccine effectiveness over time, especially when acellular vaccines were used for primary doses and boosters, and pathogen adaptation to the immunity conferred by vaccines have been proposed as possible causes of the resurgence.
Analgesic tolerance has been invoked to explain such declines in opioid effectiveness over time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com