Our work presents a kinetic model for analyzing the effect of quasi-specific sites during the target DNA search process and provides insight into how much this effect impedes Egr-1's search process in the nucleus.
Endogenous unsaturated aldehydes are found in high amounts in chronic obstructive pulmonary disease patients and are involved in the promotion of inflammation, so the exogenous analogues in smoke may have similar effects impeded by glutathione derivates.
Mutations in these genes are recessively inherited and usually result in a loss-of-function effect, mainly impeding mitochondrial function and turnover.
This leads to peripheral arteriolar constriction and a decrease in oxygen supply to the site of the wound, which in turn has the effect of impeding the wound-healing process and increasing susceptibility to infections (Jørgensen et al. 2005).
Second, a GST would also replace a welter of state taxes and other levies that serve, in effect, as protectionist barriers, impeding a true internal market in India.
In order to justify blocking a merger, the court said, the commission had to show that it would have a "direct and immediate effect" of creating or reinforcing an existing dominant position, and that this effect "lastingly impedes effective competition".
As in most movements, the conservation movement includes those on the more extreme side, which can have the undesirable effect of impeding all progress.
Antibodies can also exhibit antitumor effects by impeding angiogenesis in tumor or supporting stroma.
The untoward effect like extra hepatic effect greatly impeded T3 application to treat NAFLD.
Importantly, this effect occurs without impeding the effects of the ligands that ordinarily may act to drive thermogenesis in WAT (the intermediate and low affinity binders).
Moreover, 17β-estradiol enhanced escitalopram's efficiency in ameliorating menopausal-like depression, via exerting synergistic neuroprotective and serotonin reuptake transporter modulatory effects, without impeding escitalopram-mediated cognitive improvement.
