Sentence examples for in each escalation from inspiring English sources
The inclusion of six patients per dose group in each escalation step provided an 80% probability that at least one patient would report an adverse event that has an underlying incidence rate of 24%.
He added that even in Israel, after each escalation in the level of terrorist threat, it had taken several months for people's fears to abate.
MCF-7 cells were selected for progressive resistance to doxorubicin or paclitaxel as previously described [ 35] except that an aliquot of cells was stored before each escalation in drug dose.
In this study, a planned cohort size of 12 evaluable patients in each dose escalation cohort was used, rather than the usual six.
The sequence of patient enrollment in each dose-escalation cohort is shown in Table 4. Based on the observed toxicity, the MTD was determined to be bosutinib 300 mg per day plus capecitabine 1000 mg m−2 twice daily on days 1 14 of each 21-day treatment cycle, with no DLTs observed for the two patients treated at the MTD during the dose-escalation phase.
At least 16 people have been killed in the biggest escalation in violence in the Kashmir region in years.
In each city, de-escalation training, which instructs officers how to resolve threats without the use of force, has reduced levels of police violence and killings.
On the whole, the mean treatment duration and cumulative dose of oxaliplatin administered during each grade escalation in J-PMS were similar to those in EFC2962 and EFC4584 studies, including the escalation from grade 0 to 1 or 2 and from grade 1 to 2 (Fig. 1).
For these patients, initiation of RRT results in a considerable escalation in both the complexity and associated cost of care.
Six patients in each group had dose escalation, three of those in the days 1 3 60-mg group subsequently had dose de-escalation.
19 20 The inconsistent results mentioned above might be explained by the different proportion of patients who might benefit from infliximab dose escalation in each study.
