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Two to four mutations were present in each AML patient [ 34].
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In Figure 2B, transcripts are depicted as empty circles if they were not differentially expressed in the comparison between each AML subtype and the other AMLs, while they are filled in blue or red, if they are down- or up-regulated, respectively.
This indicates PRL-3 could play a pathological role in leukemogenesis in AML, in particular, FLT3-ITD positive AML.
In this study, we have explored sPRDM16 SUMOylation in AML in vivo and in vitro.
However, the 95% CIs successively widened as a result of the reduced number of studies/RRs that were retained with each increase in AML significance level.
However, the exact role of Klf4 and HDACs in leukemia, particularly in AML, is unclear.
IDH1/2 mutations are associated with prolonged survival in glioma and in ICC, but not in AML.
Lymph node swelling is rare in AML, in contrast to acute lymphoblastic leukemia.
Over time, differentiation block develops in these animals, resulting in AML [ 12].
Little is known about the role PTPs may play in deregulated signal transduction in AML.
Finally, lower socioeconomic status is associated with higher TRM in ALL but not in AML.
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