Sentence examples for in dsg from inspiring English sources
As active PLK4 destroys itself quickly via its phosphodegron located on the L1 linker region, stabilization might be achieved via a masking of the DSG motif upon STIL binding to L1 and a concomitant block in DSG recognition by βTrCP.
Accordingly, LiOH-KOH peritectic mixture, with a melting point of 315 °C and an enthalpy change of 535 kJ/kg, has been reported as attractive solution for the saturated storage module in DSG plants.
This implementation of community formation avoids the overhead of message exchange occurring in the group formation in DSG [13].
Further, unlike group formation in DSG, where a clusterhead of group maintains the list of member nodes, community formation is decentralized and there is no clusterhead.
"I have been incredibly fortunate to have worked with him through my role in DSG, and I always know I can count on him for helpful advice and unwavering support.
There was also correlation between reduction in Dp staining and reduction in Dsg staining.
Such TDP-43 homodimers were similarly observed in DSG-treated Hela cells, neuroblastoma M17 cells and mouse brain (Fig. 2B).
We observed that TDP-435 F − L formed homodimers to the same extent as TDP-43WT in DSG-treated cells (Supplementary Material, Fig. S2E), suggesting that the formation of TDP-43 homodimers is independent of DNA/RNA binding.
Upon analysis of TDP-43 by denaturing SDS PAGE, it was observed that TDP-43 in non-cross-linked cells migrated at the expected molecular weight of a monomer (∼45 kDa), whereas the SDS-stable TDP-43 in DSG-treated cells migrated at the expected molecular weight of a homodimer (∼90 kDa) (Fig. 2A and Supplementary Material, Fig. S2A).
However, it is unclear why the cleavage plane is restricted to the deep epidermis in PV since in PF Dsg 1 autoantibodies cause superficial blistering (Fig. 10).
In human studies on cancer treatment, in contrast, DSG was applied intravenously at much higher dosages and was still generally well tolerated [ 37, 38].
