For example, in dose model 7 the lumbar-disc compressive force is equally weighted (linearly) as the respective action duration, and this weighting is varied (force to the power of 2, 3 and 4 in the dose models 8 to 10).
Errors in estimating the RDD values used in the dose model may explain why the model made little difference in determining risk.
That means, the lumbosacral-disc compressive force is weighted overproportionally (squared as in all dose models 2 to 6) in relation to the respective duration of materials handling or intensive-load posture.
No shift-dose thresholds are considered as in all dose models 4 to 10. - Dose models 7 to 10 differ from dose model 5 only in the weighting of the compressive force in relation to the respective action duration.
Second, breast composition is a function of breast thickness in the dose model, and will thus incorrectly vary for RP and FP.
No shift-dose thresholds are considered as in all dose models 4 and 10. *Remark: There is no dose model that shows the best goodness of fit in all four case groups.
This may play a role in the elevation of some osteoclast parameters (which are not increased in the low dose model).
OCDF was not effective at the doses used in this animal dose model.
In a high infection dose model, the broiler chickens were orally infected with individual doses of 2,500 freshly prepared oocysts.
A detailed description of the dose model is provided in Additional file 1: Dose Model Appendix.
