Sentence examples for in dose escalation from inspiring English sources

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Interest in dose escalation in this setting may necessitate more advanced RT techniques, such as intensity modulation.

In dose escalation trial, for prostate cancer patients, zero CTV PTV margins towards the rectum are often applied in the boost phase in order to avoid excessive dose delivery to the rectum.

Furthermore, PFS and OS did not show any improvement in dose escalation of cetuximab.

Dose limiting toxicities were observed in dose escalation trials but a maximum tolerated dose was not established.

This problem is also likely to be increased in dose escalation for larger tumors or multiple metastatic tumors.

The predictive performance of the model was good as evaluated by predicted AUC values being within ±20% of the observed clinical data in dose escalation scenarios.

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Of the six treated patients, three received anti-CEA CAR-T cells alone in dose-escalation fashion (108, 109, and 1010 cells), whereas an additional three patients received the maximum planned anti-CEA CAR-T cell dose (1010 cells × 3) along with systemic IL-2 support.

MTD was defined as one dose level below the maximum achieved in dose-escalation.

MTD was defined as one dose level below the maximum achieved in dose-escalation or by chronic toxicities in the multi-dose trial phase of the study.

In dose-escalation Phase I trials, BI 2536 was well tolerated [ 18].

The maximum tolerable dose could be established in dose-escalation studies.

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