We focused on channels from the TRP family because many of these channels fit this profile and because they function in diverse modes of sensory transduction.
For instance, synaptotagmin-1 appears to bind to the SNAREs in diverse modes, including an interaction with the syntaxin-1/SNAP-25 hethatdimer that promotes vesicle docking [42], [51], but the exact nature of these interactions and the corresponding differences between synaptotagmin isoforms remain unclear.
CTCF regulates transcription in diverse modes, such as promoter activation and repression, silencing, constitutive and methylation-dependent chromatin insulation.
In the case of c-di-GMP, several protein types that bind this ligand via diverse modes have been discovered.
It is difficult to assess the effectiveness of pharmacological agents in localized scleroderma, owing to various factors: rareness of the disease, heterogeneity of its severity in different population studies, difficulty in establishing controls, diverse modes of evaluation for improvement and absence of serological markers for activity [ 2, 13, 14].
> -wrap-foot> likeNAs, like miRNAs, play crucial roles in epigenetic control, with diverse modes of action and functional consequences.
Moreover, this high-resolution map reveals three distinct and novel MT distribution processes in branched cilia, suggesting diverse modes of ciliary protein transport and delivery.
Here we present the first comprehensive review and analysis of EFE, including its discovery, sequence diversity, reaction mechanism, predicted involvement in diverse metabolic modes, heterologous expression, and requirements for harvesting of bioethylene.
It needs to be noted, however, that evidence to the contrary has also been described and that the presence of fast ionotropic nicotinic ACh receptors suggests that the discussion about the presence or absence of volume transmission may be more productively reframed in terms of multiple and diverse modes of neurotransmission.
In this review, we discuss the diverse modes of translational regulation by 3′-UTR-binding proteins and the experimental and conceptual advances provided by current high-throughput technologies.
Apparently, solutions to this problem evolved multiple times, as judging by the diverse modes of cytokinesis seen in modern eukaryotes.
