Despite of the German-specific implications, a comparison of the relevance of indirect comparison in the German early benefit assessment with HTA processes in England, France and Scotland is not feasible due to differential submitted comparisons and a diverging level of public transparency.
In summary, all five indirect comparisons are not comparable between Germany and France due to different submitted comparisons and a diverging level of public transparency.
However, time-course experiments revealed that the overall effect of fibronectin was to decrease IL-8 secretion per cell, as after 72 h IL-8 levels in fibronectin-coated wells did not continue to diverge from levels in BSA-coated wells despite the presence of more cells.
Despite their diverging paradigms and levels of abstraction, these languages have in common, that their users have to deal with textual programming principles.
Figure 2 shows that, following stress onset, cortisol levels diverged in the groups: control subjects exposed to stress showed a clear increase, whereas both CD subgroups showed declines over the same period.
Research that has addressed this distinction has found that factors diverge in their level of association with the two dimensions.
Current data on sRAGE levels in CAD are diverging and sRAGE may be influenced by several other factors, which is why precaution must be taken with the drawn conclusions.
Meanwhile, inequality levels diverge across countries (higher in the US and in Belgium, extremely low in Quebec).
In diversified firms, diverging interests of the corporate and business unit level in the keep-or-sell decision constitute a central barrier to active licensing.
However, the q-value thresholds for Hsp68 (0.058; P13 > P22), Fst (0.061; P13 < P22), and Treh (0.061; P13 < P22) were low enough as to suggest that these three candidate genes also diverged in gene expression levels in our populations.
At week 2, the relative levels of EM and WT virus are similar across the groups, but by week 3 the levels diverge, with more EM virus in the KP9-only vaccines (1-way ANOVA p = 0.0207, Fig 2F).
