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Interestingly, complete loss of Tnnt2 resulted in distinctive effects on diastolic Ca2+ concentrations and on the amplitude of the Ca2+ transient.
Overexpression of these two splice forms resulted in distinctive effects on various aspects of cellular functions including gene regulation patterns, alteration of growth rate, migration and morphology and susceptibility to selenium-induced toxicity.
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In view of these distinctive effects, it might be informative to study combinations in different clinical scenarios or employ them in sequence; studying the combination of an FTI with ICI182,780 for early treatment of ER positive breast tumours and reserving combinations with either Tam or a selective AEBS ligand, such as the BMS-217380-01 [ 28], for more resistant disease.
In light of the distinctive effects of claudin-5 on the nervous system, we present the elaborate network of roles that claudin-5 plays in ischemic stroke.
In light of the distinctive effects of STAT3 on the regulation of metabolism and immune responses, we present the elaborate network of STAT3 in obesity.
These distinctions accord with widely held moral instincts, but the Abhidharma philosophers needed a full, causal explanation for why the successful results of physical actions bring about their distinctive effects in one's consciousness.
In addition, several lines of evidence suggest that adjacent acidic aa residues in disordered regions have distinctive effects on SDS/PAGE mobility [ 27– 29].
Immunization with different influenza viral strains produce distinctive effects in terms of cross-neutralization and the peripheral B cell repertoire, which are related with the degree of exposures to such variants.
It can be assumed that even minor changes in the wear rate have distinctive effects on the amount of accumulating wear particles.
These distinctive effects imply that miR-34a exerts roles in multiple tissues through targeting FGF signalling.
Distinctive effects of specific GAL4 lines might be attributed to differences either in the strength, the spatial or the temporal GAL4 expression profiles in the FE throughout oogenesis.
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