Sentence examples for in distinct models from inspiring English sources

The two-layered modelling approach of openEHR allows clinical information to be specified in distinct models, called archetypes [ 18].

These professional identities are based in distinct models of care, different skill sets, diverse economic circumstances and competitive political agendas.

In addition, upregulation of these miRNAs observed in distinct models of neural differentiation strongly suggests that apoptosis-associated miRNAs may play a role in differentiation.

In view of a long list of successful experimental intervention studies in distinct models, trophic functions of ASC may be more relevant than stem cell potential in mediating osteoarticular repair.

Overall, this study suggests that there are common pathways of epigenetic dysfunction in distinct models transformed by arsenic, cadmium or MNU, which target both individual genes as well as larger chromosomal regions that contain many genes.

Next, we characterized the expression of proapoptotic miRNAs, including miR-16, let-7a and miR-34a in distinct models of neural differentiation, including mouse embryonic stem cells, PC12 and NT2N cells.

Moreover, mTOR overactivation has been shown to cause increased mitochondrial biogenesis and accumulation of reactive oxygen species in distinct model systems[36], suggesting that the activation of mTOR pathway might be responsible for the detrimental effects of MEF2C activation and vice-versa to the beneficial effects of MEF2C depletion in the mechanically overloaded hearts.

Serpins have been shown to be involved in a remarkable diversity of physiological processes in humans and in distinct model animal systems [ 3].

In this issue of Critical Care, Lutterloh and colleagues [ 1] tested roles for RAGE in two distinct models of severe infection in mice: (a) that induced by cecal ligation and puncture and (b) overwhelming infection with Listeria monocytogenes.

Although these reported effects may not be solely attributable to CGRP, we have provided substantive evidence that local CGRP plays a pivotal role in the sensitization of joint nociceptors in 2 distinct models of OA pain.

Macrophage differentiation, osteoclast differentiation, macrophage priming, and cytokine level were compared by unpaired t tests with GraphPad InStat Version 3.0 (GraphPad Software, Inc .. To determine whether specific inhibition of c-Fms provides benefit in autoimmune arthritis, we explored the effects of GW2580 in several distinct models of RA and compared them with the effects of imatinib.