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These findings indicate that during evolution the combination of integral membrane transport proteins with either a periplasmic solute-binding protein or a cytosolic ATPase, or both, have resulted in distinct classes of transporters with unique architectures and properties.
CB and PV are expressed in distinct classes of projection neurons in the thalamus and distinct neurochemical classes of inhibitory neurons in the cortex.
In addition to the classification in distinct classes, we have used letters to classify each B3 domain according to the position in the protein, i.e., A indicates the closest B3 domain to the protein's N-terminal region.
Subsequent differential duplicate loss events in the three descendants resulted in distinct classes of gene loss patterns, including cases where the genes retained in the three descendants are paralogs, constituting 'traps' for ortholog prediction algorithms.
The reported permutations in N-MTases concern only the segments within the catalytic domain, while the unrelated TRDs were acquired or evolved independently in distinct classes [ 20].
As similar diseases are more likely to share associations than diseases in distinct classes, we expected the SVN to be organized in a modular fashion.
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Another interesting finding is that the brain regions can be divided into distinct classes in terms of their intra- and inter-module connectivity patterns.
First, the p-aaRSs appear to be divided in two distinct classes, their structures having nothing in common (on all, 1D, 2D and 3D, levels).
Based on their primary structure, these toxins can be classified in tree distinct classes: class I is found in Elapidae snakes venom; class II is found in the Viperidae family of snakes; and class III that was identified for the first time in the bee venom.
These findings suggested the possibility that increased expression of specific ribosomal proteins in unique tissues might lead to the heterogeneous ribosomes in the distinguished cell tissues by specificities in translating distinct classes of mRNAs.
In fishes, distinct classes of 5S rDNA have already been found in several Actinopterygii and Elasmobranchii.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com