Sentence examples for in distant stage from inspiring English sources

Etzioni et al (2008), in a population-based simulation model, projected a 52% decline in distant stage incidence with PSA screening.

Similarly, Sherman et al (2004) reported reduced 10 year survival in distant stage vs localised disease in a group of approximately 4500 borderline ovarian cancer patients.

Compared with patients without diabetes, we observed that colorectal cancer patients with pre-existing diabetes had significantly higher risk of total mortality (HR=1.20, 95% CI: 1.17 1.23 for patients in all stages, HR=1.25, 95% CI: 1.21 1.29 for patients in localised or regional stage and HR=1.12, 95 CI: 1.06 1.18 for patients in distant stage) after adjusting for potential confounders.

Similar trends were found in distant-stage right-sided CRC.

These results support the prognostic significance of KRAS-mutation status beyond its now established role as a predictive marker in distant-stage CRC.

One explanation for the increase in distant-stage and distant-stage right-sided colon carcinoma among Hispanics may be the persistently low rate of CRC screenings in Florida.

Moreover, scientific investigations of molecular markers are warranted to fully understand the biological mechanisms behind varying trends in distant-stage and right-sided CRC.

There was a slight tendency for the associations to be stronger in distant-stage, rather than localized or regional, cancers but, again, these differences were not larger than would be expected by chance (see Additional file 4).

In a recent meta-analysis, Lin et al (2011) reported that the presence of a KRAS mutation had a positive likelihood ratio of 2.0 (95% CI: 1.45 2.76) for predicting non-response to anti-EGFR in distant-stage CRC.

There was a consistent significant increase in the incidence of distant stage CRC in Hispanics (annual percent change (APC) of 1.26 and 0.90 in males and females), whereas rates in non-Hispanics decreased significantly during the same time period (APC −1.36 and −1.28, respectively).

Patients with localized melanoma have the 5-year survival rate of about 98%, but the rate radically declines in regional and distant stage disease to reach 63% and 16%, respectively [ 3].