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In direct replication the original methodology is reproduced as faithfully as possible; in conceptual replication the original research question is tested again with different methods.
The results were consistent in direct replication genotyping in an independent set of 5419 cases and 47 687 controls [OR = 1.13 (95% CI: 1.06 1.19), P = 4.3 × 10−5].
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In the Dual-task condition, the same group of observers was tested in a direct replication of Experiment 5.
In addition, direct replication of findings across countries is possible.
Building up detection capacity in these countries by direct replication of the systems existing in developed countries is not a feasible approach and instead requires "leapfrogging" to the deployment of the newest diagnostic systems that do not have the infrastructure requirements of systems used in developed countries.
Direct replication in some of the loci showing significant differences in associations according to ER or PR status provides further support for the hypothesis that intrinsic subtypes of breast cancer should have different etiologic pathways; thus, the polygenic component of these subtypes of breast cancer should be different [ 27].
This could be achieved in numerous ways, from direct replication to adaptation with another sign language.
At first these efforts aimed to directly replicate SNP-specific associations (by direct genotyping only the candidate SNP in a second population, rather than performing an independent GWAS), but it soon became apparent that achieving direct replication in an independent cohort posed significant challenges.
Although about 350 ARS have been estimated in the genome of S. cerevisiae, only a subset of them appears to direct replication initiation in the S-phase [26], [41].
In the first stage, we attempted to replicate 20 of the 29 exact published SNPs (i.e. direct replication) available in the HUFS dataset.
For years, it was extremely difficult to publish a direct replication, or a failure to replicate an experiment, in a good journal.
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CEO of Professional Science Editing for Scientists @ prosciediting.com