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Many retrotransposons retain the ability to move (transpose) to new locations in the genome, a potentially deleterious phenomenon that can result in direct disruption to coding regions [ 2, 3].
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Feedback mechanisms between APP and other misregulated AD associated genes may serve to also reduce PuF activity in concert with direct disruption of APP-PuF interaction.
However, an alternative possibility is that mutations in Atmin may lead to direct disruption of the actin-myosin cytoskeleton, since abnormal cytoskeletal organization was observed in the homozygous kidneys.
"For anybody that wants to follow in our footsteps, this is a direct disruption of freedom of speech, this is like a muzzle," Fara said, adding that they will keep fighting the ruling.
As shown in Fig. 5 A, Dynasore did not inhibit the action of PLO by direct disruption of the CDC or by protecting the red blood cells.
And two important industries in the region, tourism and transportation, are suffering direct disruptions that will be hard to overcome.
Regional shape compression and FA reduction in these tracts may indicate the loss of neuronal axons or loss of connection with the cortex, suggesting a disruption in direct or indirect connectivity of the temporal lobe with the frontal, parietal, and occipital lobes as well as the cerebellum.
Strong detergents contain chemicals that come in direct contact with your vagina causing disruption of normal flora.
The Guardian has learned that groups engaging in direct action are likely to break off from the march at different points, causing disruption which may become a focus of police attention.
Dry in direct sunlight.
Place in direct sun.
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CEO of Professional Science Editing for Scientists @ prosciediting.com