Exact(26)
28 Not only do estimates of the prevalence of diabetes depend on which screening test is used, administering HbA1c instead of FPG affects estimates of the prevalence of diabetes differently in different racial or ethnic groups.
In addition, differences in insulin clearance in different racial groups (21, 22) could confound the insulinogenic index data.
Differences in the efficacy and safety of various drugs in different racial groups have been well documented and can be attributed to differing rates of comorbid conditions, concomitant medication use, and underlying genetic variations in the enzymes involved in drug metabolism [ 27].
By itself, therefore, the study could not claim differential drug efficacy in different racial groups, and marketing BiDil as a racially targeted therapy potentially limited access of non-African Americans to a treatment from which they also might benefit.
These screening disparities may contribute to the known differences in colorectal cancer incidence and survival in different racial groups [ 18, 19].
But though much less is known about them, they may be caused by different genes in different racial groups, Dr. Risch says.
Similar(34)
The age-standardized distribution of the risk factors in men in the different racial groups is shown in Table 2. Obesity (BMI> = 30.0) was least common in Japanese Americans (7.8%), but was 15.5% in Whites, 19.5% in Latinos, 21.4% in African Americans and 31.8% in Native Hawaiians.
The procedures were carried out in two different racial groups in a variety of settings, so that the findings are likely to be valid for the general population.
That's consistent with the idea that the current party affiliation differences between age groups has disadvantaged Democrats in midterm elections, while the differences in turnout by different racial groups likely don't have much of an effect.
Differences have been observed in people from different racial and ethnic groups and in patients who have HIV and end-stage renal disease.
However it is also important to note that large vaccine evaluation trials (e.g., recent STEP trial) are invariably a composite of subjects from several different geographically disparate clinical sites, and consequently, failure to account for CCL3L1-CCR5 genotype at these smaller sites in subjects with different racial backgrounds might result in confounding of a larger multicenter trial.
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