Exact(4)
The variable VAFs in different mutations from ctDNA implied variable clonality of different mutations.
Conceivably, different pathogenic mechanisms may be involved in different mutations.
Each tumor, and also each glioblastoma, evolves as a result of stochastic and environmental processes in different mutations [ 39].
We suspect that the mixed clones are likely the result of sorting multiple cells into a single well during the FACS process or ongoing pCas9 activity after cell division, resulting in different mutations in each daughter cell.
Similar(56)
As shown in Supplementary Data 6 and Supplementary Fig. 6, variable dynamic changes were observed in different mutation clusters from each individual patient.
However, as shown in two reports [ 24, 25], racial factors might also result in different mutation frequencies at specific genomic locations [ 27, 28].
Divergent adaptation may proceed via different mutations in different localities such that particular outliers are not highly consistently observed across population comparisons [ 12].
In case different mutations in the same region were selected in the two populations, rMHH would show a small value, but rHH would not.
Richie says the images in the zine "take on a bloody, carnage-like savagery in which my man-eating ways are on full display in my different mutations, placing myself in different fantasies, dark places including myself getting de-robed in a cemetery in Queens". .
86, 87 Other examples demonstrate that, in fact, different mutations can be present in close proximity.
Allelic heterogeneity is the phenomenon in which different mutations at the same locus (or gene) cause the same disorder.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com