Standardizing LAP technology for MRD detection is complicated because aberrant immunophenotypes may not only differ from patient to patient but also within a patient, often resulting in many different LAPs (illustrated in Supplementary Figure 1).
Consistent with a retroposition event, S-LAP 7 is intronless, unlike its likely progenitor S-LAP 4, and these genes reside in different genomic regions (2R: 50C5 and 3L: 67E4, respectively).
Furthermore, the two fractions differed in specific activities perhaps reflecting a partition of different S-LAPs that may be directly related to functional diversification between them (see below).
To investigate the impact of different time-laps before sampling on IL-10 concentrations in patients, we compared IL-10 concentrations over deciles of hours before sampling.
This study experimentally determines the tensile failure load of the nanocomposite adhesive – obtained by adding nanostructures to the adhesive – using four different methods in single-lap joints.
In the first part of this study, single lap joints in many different geometric and material configurations were tested in tension with high strength steel adherends.
Single lap joints in many different geometric and material configurations were analysed using finite element analysis and tested in tension.
In this weekend's "Your Money" column, I took a weeklong lap of New York City, staying in five Airbnb rentals in five different neighborhoods.
All these factors contribute to, often, large differences in the applicability of specific LAPs for different leukemia cases.
Korsgaard's response comes in three laps.
