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For example, there may be geographic differences in the racial or ethnic compositions of populations served in different centers, or there may be regional differences in diet or other behaviors that lead to expected variation in characteristics such as weight or BMI.
Registry cohorts like these, are, however important in the determination of patient clinical course and the possible differences in the management of patients in different centers.
In part this may be due to selective assignment of patients to new technologies or services relative to the standard care in different centers.
In this respect we should also stress that samples collected in different centers were used in our study, which reduces the chance for such biases.
In many cases, dosimetry is feasible, and several therapies exist in which dosimetry is being performed on a fairly standardized basis in different centers and countries.
Technique of exit-site care is variable in different countries, and regular use of mupirocin ointment at the exit site is practiced in different centers.
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In addition, the laboratory procedures and brands of reagents used in the different centers may differ in sensitivity and specificity; comparisons between them are not straightforward.
Of note, the scale relies on the use of biomarker cutoffs that might differ in the different centers.
Patients arriving in hospital less than 180 minutes post-injury requiring full trauma team activation in four different centers were included in the study.
The World Health Organization study of psychological disorders in general health care in 15 different centers indicated that for the GHQ-12 substantial factor variation between centers exist.
Barrel pixel modules are in production since spring/summer 2015 in five different centers.
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