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The role of transcriptional networks in determining mode of action of small molecules is undoubtebly growing, thanks to availability of more detailed gene network models and to the ever increasing amount and quality of GEPs.
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We show that levels of miR-200 are increased in melanoma cell lines compared to normal melanocytes and that miR-200 family members play a role in determining modes of tumor cell migration.
The single punch shear (SPS) and double punch shear (DPS) specimens have been used in the past for determining Mode II fracture toughness of engineering materials.
Initial validation of the localised experimental numerical technique (LENT) shows that applying experimental data to a numerical model does give reasonable agreement thus far in the established trends, and hence LENT is promising for use in determining mixed mode strain energy release rates and mode mixity ratios.
The mode shapes were extracted, and the eigenvectors were used in determining the mode shape equations using nonlinear regression.
This method allows to determine mode dispersions in the structure with a planar periodicity with high accuracy except regions of dispersion branches intersection, where mode coupling may be occur.
Your "focus level" is a large factor in determining your mode of thought (or of consciousness) at any moment.
But does the environment have a role in determining which mode the AGN's are in?
To examine the influence of strain rate, bone mineral density, and age in determining the mode by which human Achilles tendons fail.
Recent investigations into the nature of molecular mimicry with regard to protein ligand interactions are described, along with applications in determining the mode of action of enzyme inhibitors.
Nevertheless, not much progress has been made regarding the realistic treatment of collision processes that are critical in determining macroscopic mode of fluidization.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com