Because the changes in parameter values demonstrated clear trends that followed evolutionary advancement, we proceeded with an in-depth correlation analysis.
The FTLD syndrome in the European G4C2 expansion carriers was most often characterized by behavioral disturbances (95.7%), which was in line with our observations from an in-depth genotype phenotype correlation study in the Belgian C9orf72 carriers [Van Langenhove et al., 2012b].
The pearson correlation matrix for the six matched samples is given in Figure 4. Coverage depth correlations for the same site across individuals was highest for Agilent, followed by Nimblegen and Raindance.
Therefore, an additional in-depth study about correlation between the location of nsSNPs and functional site of proteins is necessary.
Due to the relatively low coverage of these data sets (generated in 2008), we were unable to perform an in-depth study of correlations between transcriptional activity and nucleosome positioning, in particular for promoter regions.
Additionally, more in-depth investigations on the correlation of the percentage of Her2/neu-immunopositive GCs with clinical outcomes may help to improve predictive diagnostics.
These three examples demonstrate the important role of colloidal synthesis and in situ spectroscopy measurements for in-depth analysis of structure reactivity correlations.
Overall, our method allows a more in-depth analysis of the correlations between epigenetic changes than conventional methods.
Further, in-depth analysis indicated a positive correlation between the serum PGE2 level and tumor COX-2 expression (Pearson's correlation coefficient, 0.900; P<0.001, two-tailed).
The marked horizons/geological boundaries were used for well correlation in depth domain and also used for seismic interpretation in time domain to find the lateral facies continuity.
In this context, a more in depth analysis of the correlation between immunohistochemically and FACS assessed CD133 positive tumor cells would be of utmost importance.
