We demonstrate both intercellular and transcellular pathways for different active compounds, together with in-depth concentration profiles reflecting the detailed skin barrier architecture.
Analysis of this temporal dispersion curve the fluorescent temporal point spread function (TPSF is used to obtain information of the in vivo fluorophore depth, concentration, and lifetime.
Results obtained for these two thickness values are well correlated with in-depth Pt concentration profiles determined by energy-dispersive X-ray analysis (EDX).
The action of high-intensity beam of carbon ions on a silicon sample is studied by means of a numerical modelling revealing formation of the in-depth carbon concentration profile in crystal lattice of silicon.
Moreover, our recent depth profiling XPS experiments showed that C contamination is mostly located only at the topmost 2 to 3 atomic layers because going down in depth, the relative concentration of [C]/[Sn] was about 0.1, which was almost constant up to the Si substrate.
In addition, it is suggested that morphological properties such as average slope gradient, drainage area and drainage density could have implications for the fate and stability of C stored at depositional sites through changes in the in-depth variability of C concentration in sediments and in the concentration of two measured C fractions.
Increasing the exposure time to both air and oxygen plasma brought about quantitative rather than qualitative changes (increase in edge recession, growth of pits in diameter, depth and concentration).
When the co-doped film is obtained by potentiodynamic method, its anion composition is not homogeneous in depth, there is a concentration gradient of the doping anions.
The effect of three important synthesis parameters was studied in-depth: carboxymethylcellulose:starch ratio, solute concentration and absorbed dose.
Variability between cells may be due to differences in sequencing depth, RNA concentration, GC content, and amplification biases, among others.
Finally, we demonstrate that long-term climate and climate variability are reflected in the depth and concentration of the calcic soil properties.
