These immunological "side" effects of chemotherapy are desirable, and their in-depth comprehension will facilitate the design of novel combinatorial regimens with improved clinical efficacy.
Optimizing system design and operation of reverse osmosis (RO) systems requires an in-depth comprehension of the intrinsic tradeoff between RO mass transfer kinetics and energetics.
The fundamental understandings of the early stage of shish kebab crystallization, transition process from random entangled chains network to stable shish kebab cylindrulite, and the role of long polymer chains on shish kebab formation, are very helpful for in-depth comprehension of shear-induced shish kebab in realistic processing.
Rational design of nanoparticles has become a prevalent trend requiring an in-depth comprehension of the chemical and physical characteristics of their building blocks.
Clarification and in-depth comprehension of these pathways may unveil needed therapeutic potentialities that could be applicative to both aging and age-related diseases.
Mathematical modeling and computational analysis of biological systems nowadays represent an essential methodology, complementary to conventional experimental biology, to achieve an in-depth comprehension of the functioning of these complex systems [ 1, 2].
From a long-term perspective, an in-depth and systematic comprehension of internal physics in OSCs is essential for a lasting development of the field.
First, we did not investigate in-depth the recall and comprehension aspects of informed consent in the selected clinical studies.
The development of the VAPI followed a rigorous and recommended standard procedure [ 30], based on in-depth interviews and subsequent comprehension testing with vaccinated adults, to allow the subjects' full perception regarding their local reactions to be measured.
Thus, 'implicit' here is defined rather by an in-depth capacity to demonstrate theory of mind skills, convey comprehension of social life and reason about and spontaneously elaborate on a given multiple-choice reply.
Comprehension of complex systems is essential for in-depth understanding of environmental issues.
