Those problems require comprehensive, in-depth and systematic research and testing.
The studies of the effects of friction force, connectors, etc. are not mature and lack in-depth and systematic work.
From a long-term perspective, an in-depth and systematic comprehension of internal physics in OSCs is essential for a lasting development of the field.
An equally in-depth and systematic analysis of TLR diversity is lacking despite numerous independent reports of a growing number of SNPs within these loci.
Therefore, both safety and efficacy of iPSC warrant in-depth and systematic assessment in experimental animal models.
Without a more in-depth and systematic examination of inequities underlying asthma prevalence, these studies may fail to provide the evidence required to inform interventions targeted at key levers in the pathways to inequity.
During our fieldwork we conducted an in-depth and systematic study of six CCGs and local clusters (also called localities) in the East of England region (sites A, B, C, D, E and F).
Without more in-depth and systematic examination of inequities underlying asthma prevalence, quantitative studies may fail to provide the evidence required to inform equity-oriented interventions to address underlying circumstances restricting opportunities for health.
The offspring underwent in-depth and systematic assessments and were prospectively followed up at several time points (scheduled at weeks 1, 2, 4, 8, and 12 for the UHR offspring) during the first 3 months and then yearly (up to 2 years) or anytime there were changes in symptoms.
Further advances in the development and application of the hiPSC technology for personalized therapies, however, require an in-depth and systematic evaluation of hiPSC-CMs and their maturity with a quantitative comparison with hAdultV-CM, which can be facilitated by in silico investigations such as the one presented in this study.
