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In defiance of the odds, an insightful director could go for characterization, subtext and truth.
In defiance of the odds (thirty out of the thirty-three teams previously in their position — down 2-0, homeing have — have gone on to lose), and in spite of my usual pessimism (both native and adoptive), I still think they have a chance.
We learn that John/Joan is a hardworking family man in Canada named David Reimer: in returning to his malehood, he decided that he didn't like the name Bruce and so rechristened himself after the biblical hero who, in defiance of the odds, slew the giant Goliath.
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Somehow, in defiance of all the odds, we've made something that's brilliant.
It has been estimated that 149 of Labour's 232 constituencies voted Leave, in defiance of the party's wishes and at odds with the overwhelming majority of Labour's mainly professional membership.
But for the most part, and in absolute defiance of the odds, "Stranger Things" honors its source material in the best way possible: By telling a sweet 'n' scary story in which monsters are real but so are the transformative powers of love and fealty.
Development in Defiance of the Washington Consensus, The Guardian, April 13 , 2006
The war had endured in defiance of the democratic process.
They were arrested in defiance of the Bosnian courts.
Four out of five of them did, in defiance of the union's boycott.
Gradually bowlers raised the hand higher and higher in defiance of the law.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com