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It's windy and wet, the hills lost in deep grey fog, with only geese and oystercatchers animating the hills.
Abnormal Magnetization Transfer Ratio (MTR) or Fractional Anisotropy (FA) have been reported in the cortex of MS patients with reduced NAA and increased mI/Cr (mI- myo inositol, Cr- Creatine) ratios in deep grey matter on MRS, suggesting both axonal injury and gliosis [42].
In deep grey matter (thalamus) the two groups had similar permeability values.
ICV was added as independent variable to adjust for differences in deep grey matter volume due to differences in head size between patients.
VD patients fulfilled the brain MRI criteria for SVD [ 32], including extending periventricular and deep WMLs or multiple lacunes in deep grey matter, and at least moderate WMLs.
This structure consists of neurons formed in deep grey matter neurogenic sites such as the thalamus, and arrive to lie below the cortical neurons that migrated earlier from the subventricular zone [ 43].
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The perivascular drainage of drugs delivered into deep grey matter structures might also result in distribution into the subarachnoid space.
This relates to the relatively slow rate at which the tumour cells migrate in the deep grey matter in and around the thalamus whereas the frontal lesion would be expected to migrate γ-fold more quickly within the local white matter.
While dyskinetic CP or quadriplegia is more commonly seen following "acute near total type of asphyxia" with MRI abnormalities present in the deep grey nuclei and in the perirolandic cortex, milder forms of CP, such as spastic diplegia, are more common among those with "subacute partial asphyxia" with MRI abnormalities in the watershed areas.
Voxel based morphometry has shown its value in comparing groups of subjects in patterns of atrophy, but is prone to registration artifacts in the deep grey matter and not suitable for analysis of the pattern of atrophy in an individual subject (Bookstein, 2001; Frisoni and Whitwell, 2008).
Figure 2 shows a simulation similar to that presented in Figure 1 but the virtual tumour originates at a point (asterisk) in the deep grey matter of the thalamic region of the brain.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com