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If Zurich represented about 3percentt of the U.S. insurance market -- that is, it was on the hook for about 3percentt of the losses -- a hurricane would need to inflict about $40 billion in damage to trigger the default.
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Loss of wild-type p53 protein results in failure of radiation-induced DNA damage to trigger apoptosis events downstream p53 (Brugarolas et al, 1995).
In CF, recurrent infections and inflammatory insults result in damage to the airways and trigger the repair process [ 89].
Our simulations suggest that it is not necessary to have a sudden increase in damage in order to trigger spontaneous oscillations.
The repertoire of genes coding for secreted hydrolytic enzymes is small and this has been correlated to the biotrophic lifestyle of the pathogen in which damage to the host that can trigger defense responses is minimized.
This is consistent with the hypothesis that as aging progresses a threshold is reached where ROS levels can contribute to damage in addition to triggering a protective response.
It is conceivable that induction of ply by TIGR4 resulted in epithelial damage, which in turn led to triggering of nitric oxide production by the host cells, placing bacteria under nitrosative stress.
Damage to DNA in bacteria can trigger at least two repair systems, the ada-controlled adaptive response specific to damage by alkylation, and the recA-dependent, lexA-controlled SOS response.
Further studies suggested that damage to cells in the barrier triggered a chemical cascade that affected the neighboring cells, Case says.
Many patients suffered mild side-effects lasting a day or two and there were rare cases of more serious accidents, causing damage to the arteries in the neck, triggering a stroke.
We propose that this nicotine-induced increase in ROS likely triggered early, but undetectable damage to the ETC enzymes, thus initiating a feed-forward chain of progressive mitochondrial damage and additional ROS production.
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